Brazil, US, UK

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Soa Paulo, 3,000 deaths in the city
Health systems overwhelmed in 2 weeks


Cases, + 4,970 = 101,139
Deaths + 134 = 3,163

Eight weeks into lockdown

high temperature – this means you feel hot to touch on your chest or back (you do not need to measure your temperature)
new, continuous cough – this means coughing a lot for more than an hour, or 3 or more coughing episodes in 24 hours (if you usually have a cough, it may be worse than usual)
loss or change to your sense of smell or taste – this means you've noticed you cannot smell or taste anything, or things smell or taste different to normal

Does this increase sensitivity of infection detection, ‘a little’

App could be another 2 weeks

ENT Doctors, 20 March
Kings College group, 1st April

COVID Symptom Tracker

COVID symptom tracker study
Kings College London Zoe, Tim Spector
3.6 million users
Active cases in the UK, 252,629

59% of people who lost smell tested positive
18% of people who lost smell tested negative
50 – 70,000 cases missed
Perhaps more in the young
Perhaps more in women
Virus is causing some sort of inflammation in the olfactory nerves

COVID-19 symptom tracking app show that anosmia is a stronger predictor of coronavirus infection than fever.

An early feature

400,000 people reporting one or more symptoms between 24-29th March:
In order
Fatigue, persistent tiredness 53%
Fever or persistent cough 32%
Chest pain 28%
Persistent cough 29%
Shortness of breath 28%
Hoarse voice 24%
Loss of smell 18%
Anorexia 16%
Diarrhoea 16%
Confusion 14%
Abdominal pain 13%
Fever 10.5%

Anyone over 5 years with symptoms can have a drive through test
Results a bit slow coming back

Dying with or from COVID-19 (ONS)

1st March – 30th April

33,841 deaths involving coronavirus
95.0% had COVID-19 assigned as the underlying cause of death.
In 90.4% of cases, the person who died from COVID-19 had at least one pre-existing condition

Vaccine, Moderna, Massachusetts.
8 people given 2 doses
Producing "neutralising antibodies" in all 8
Similar safety profile to previous vaccines
Antibodies levels similar to recovered Covid-19 patients
Phase 2, 600 people to start soon
Phase 3, involving thousands in July.
Will it protect against disease?
January - June 2021

President Trump, WHO to “commit to substantive improvements.”

CDC plans sweeping antibody study to track coronavirus's spread

Centers for Disease Control and Prevention, nationwide antibody study in 25 metropolitan
testing blood from donors, June or July
tens of thousands
We have selected sites to give a broad geographical distribution throughout the country, (Dr. Graham Simmons)
US, a member country has not been completely transparent
US critique of WHO
$2 billon for developing countries
Chinese hospitals pairing with 30 African countries

Need for complete international overall
Dr Tedros agreed
Australia and South Korea agree

140 world leaders call for Peoples Vaccine
Mandatory worldwide sharing of knowledge
Global and equitable distribution plan
Diagnostics, vaccines and treatments free at point of need
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